Tenofovir Alafenamide: All You Need To Know About

Tenofovir alafenamide is an antiviral prescription medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with hepatitis B virus infection (HBV) who meet certain requirements, as determined by a healthcare professional.

Hepatitis B virus can be an opportunistic infection (OI) of HIV. An opportunistic infection is an infection that occurs more often or is more severe in those individuals who are with impaired immune systems; such as individuals with HIV, than in individuals with strong immune systems. 

The tenofovir alafenamide is also a component of several FDA-approved FDC (fixed-dose combination) tablets to treat HIV infection. The emtricitabine/tenofovir alafenamide fixed-dose combination tablet (Descovy) is also approved for HIV pre-exposure prophylaxis (PrEP).

Dosing Regimen

Tenofovir Alafenamide is supplied as a 25 mg dosage strength small tablet that you take once a day with food. You must take tenofovir 25 mg exactly how your health specialist tells you to. If you are on dialysis, on your dialysis days, take your dosage after dialysis. It’s also important to take the tablets on a regular dosing schedule in order to avoid missing doses. Do not stop taking dosage unless your health specialist tells you to. If you stop taking your medication, your hepatitis B virus infection could get worse (flare-up). A “flare-up” is when your hepatitis B virus infection unexpectedly pop ups in a worse way than before. It is very necessary that you refill your prescription on time, before you run out. If you take too much tenofovir 25 mg, call your healthcare professional or head to the nearest hospital emergency room immediately.

Before Taking Tenofovir Alafenamide:

Tell your health specialist about entire your medical conditions, including if you:

• have HIV-1 infection. Your health specialist may test you for HIV infection prior to treatment with tenofovir. If you have both HIV and HBV, and you only take tenofovir alafenamide 25 mg, the HIV virus may develop resistance and be difficult to treat.
• have an end-stage renal disease (ESRD).
• are pregnant or intent to become pregnant.
• are breastfeeding or intent to breastfeed.

Inform your health specialist about all the medications you take: 

• Keep a list that includes all prescription and OTC medicines, vitamins, and herbal supplements, and show it to your health specialist.
• Ask your health specialist about medications that may interact with tenofovir alafenamide.

Possible Side Effects of Tenofovir Alafenamide

New or worse kidney problems, including kidney failure: Your health specialist may perform blood and urine tests in order to assess your kidneys when starting and while on treatment with this medicine. Your health specialist may tell you to halt taking your pills in case you develop new or worse kidney problems.

Excess lactic acid in the blood (lactic acidosis): Lactic acidosis is a serious but rare medical complication that can lead to death. Report to your health specialist promptly if you get these signs/symptoms: weakness or being more tired than usual, being short of breath or fast breathing, unusual muscle pain, stomach pain with nausea and vomiting, or cold or blue hands and feet, feeling dizzy, lightheaded, or abnormal heartbeat.

Severe liver problems: Severe liver problems in rare cases can lead to death. Report to your health specialist right away in case you get these signs/symptoms: skin or the white part of eyes turns yellow, light-colored stools, loss of appetite for several days or longer, dark “tea-colored” urine, nausea, or stomach-area pain.

The most commonly reported side effect of tenofovir alafenamide tablets 25 mg is headache. Although, these are not the entire possible side effects of this medication. Report to your health specialist in case you have any side effect that is persistently bothering you.

Tenofovir Alafenamide may be responsible for causing serious side effects, including:
Worsening of hepatitis B virus infection: Your hepatitis B virus infection may suddenly get worse (flare-up) in case you halt treatment with tenofovir alafenamide tablets. Do not run out of your dosage. Do not stop taking your pills without first interacting with your health specialist, as they will need to assess your health on a regular basis after stopping tenofovir 25 mg therapy.

Availability & Price

In order to procure the antiviral drug Tenofovir Alafenamide, one can directly get in touch with any WHO-GDP and ISO certified pharmaceutical company or Wholesaler/Supplier/Distributor. The tenofovir price in India is absolutely reasonable and may vary depending on the generic to brand-name products. Kindly connect to us through our TOLL-FREE: 1800-889-1064 to get the Best Quality Tenofovir Alafenamide at a reasonable price. We are authentic and approved by the WHO-GDP & ISO to supply Tenofovir Alafenamide, from India. 

Note: This is only a brief summary of important deets about Tenofovir Alafenamide. Talk to your health specialist or go to full prescribing information to learn more. 

Reference:
https://www.vemlidyhcp.com/
https://www.medicines.org.uk/emc/product/2314/smpc#gref
https://www.drugs.com/cons/tenofovir-alafenamide.html